Is it better to reflect manual adjustment result to the color profile?

When manual adjustment result is considered to be a part of calibration, you should correctly reflect it to the profile. However, when manual adjustment is a just fine adjustment, it is not good to reflect it to the profile. When you use this function, it is important to know these technical details. [Reference] In the case of manually adjusted ambient light, color of printed-paper, brightness and so on., it is better to reflect the manual adjustment data to the profile. In the case of adjusting the monitor manually as a last small adjustment in a series of color management workflow, it is not better to reflect the manual adjustment to the profile.